Hello everyone,

During the last journal club meeting we decided on a couple of papers
for the next three meetings. At the next journal club meeting, on Friday
April 25th at 1:30 in Bill's office YH 3047 (note the new time and day),
we will discuss the following paper:

* "Western equine encephalitis virus is a recombinant virus" by C.S.
Hahn, S. Lustig, E.G. Strauss and J.H Strauss, PNAS 85, 5997-6001
(1988) (http://www.pnas.org/cgi/reprint/85/16/5997).

Although we will focus on this paper the following papers are also
interesting to take a look at:

* "Striking similarities in amino acid sequence among nonstructural
proteins encoded by RNA viruses that have dissimilar genomic
organization" by J. Haseloff, P. Goelet, D. Zimmern, P. Ahlquist,
R. Dasgupta and P. Kaesberg, PNAS 81, 4358-62 (1984)
(http://www.pnas.org/cgi/reprint/81/14/4358).

* "Sindbis virus proteins nsP1 and nsP2 contain homology to
nonstructural proteins from several RNA plant viruses" by P.
Ahlquist, E.G. Strauss, C.M. Rice, J.H. Strauss, J. Haselhoff and
D. Zimmern, J. Virology 53, 536-42 (1985)
(http://jvi.asm.org/cgi/reprint/53/2/536).

* "Molecular evolution of the plant virus family Bromoviridae based
on RNA 3-encoded proteins" by F.M. Codoner, J.M. Cuevas,
J.A.Sanchez-Navarro, V. Pallas and S.F. Elena, J. Mol. Evol. 61,
697-705 (2005) (http://dx.doi.org/10.1007/s00239-005-0021-7).

During the journal club meeting following this one (probably in the
first week of May) we will discuss:

* "Complementation between Sindbis viral RNAs produces infectious
particles with a bipartite genome" by U. Geigenmuller-Gnirke, B.
Weiss, R. Wright and S. Schlesinger, PNAS 88, 3253-3257 (1991)
(http://www.pnas.org/cgi/reprint/88/8/3253).

Some other papers that might also be of interest for that meeting are:

* "Sindbis virus with a tricomponent genome" by R. Fayzulin, R.
Gorchakov, O. Petrakova, E. Volkova and I. Frolov, J. Virology 79,
637-43 (2005) (http://jvi.asm.org/cgi/reprint/79/1/637)

* "Recombination between Sindbis virus RNAs" by B.G. Weiss and S.
Schlesinger, J. Virology 65, 4017-25 (1991)
(http://jvi.asm.org/cgi/reprint/65/8/4017).

During the third meeting we will discuss:

* "The fittest versus the flattest: experimental confirmation of the
quasispecies effect with subviral pathogens" by F.M. Codoner,
J.-A. Daros, R.V. Sole and S.F. Elena, PLoS Pathogens 2, 1187-1193
(2006) (http://dx.doi.org/10.1371/journal.ppat.0020136).

Some other interesting papers are:

* "Response on foot-and-mouth disease virus to increased
mutagenesis: influence of viral load and fitness in loss of
infectivity" by S. Sierra, M. Davila, P.R. Lowenstein and E.
Domingo, J. Virology 74, 8316-23 (2000)
(http://jvi.asm.org/cgi/reprint/74/18/8316).

* "High nucleotide substitution error frequencies in clonal pools of
vesicular stomatis virus" by D.A. Steinhauer, J. Carlos de la
Torre and J.J. Holland, J. Virology 63, 2063-71 (1989)
(http://jvi.asm.org/cgi/reprint/63/5/2063).

* "Extreme heterogeneity in populations of vesicular stomatis virus"
by D.A. Steinhauer, J. Carlos de la Torre, E. Meier and J.J.
Holland 2072-80 (1989) (http://jvi.asm.org/cgi/reprint/63/5/2072)

* "What is a quasispecies?" by M.A. Nowak, Trends in Ecology and
Evolution 7, 118-121 (1992)
(http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6VJ1-4B0P9VX-3M-1&_cdi=6081&_user=10&_orig=browse&_coverDate=04%2F30%2F1992&_sk=999929995&view=c&wchp=dGLzVzz-zSkzS&md5=afe8689a9981d7b471efa33fdc21f768&ie=/sdarticle.pdf
<http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6VJ1-4B0P9VX-3M-1&_cdi=6081&_user=10&_orig=browse&_coverDate=04%2F30%2F1992&_sk=999929995&view=c&wchp=dGLzVzz-zSkzS&md5=afe8689a9981d7b471efa33fdc21f768&ie=/sdarticle.pdf>).

I will send separate announcements for the last two meetings, once we
know when we will meet.

Best wishes and happy reading!

Peter