Journal Club

Brownbag #79 (9/5, Fri, 12:30p, YH2050)

Dear Colleagues,

At tomorrow's journal club we shall review a theory paper titled "Single Polymer Molecules in a Protein Nanopore in the Limit of a Strong Polymer-Pore Attraction" by Krasilnikov et al.

Reprints are available online at: http://dx.doi.org/10.1103/PhysRevLett.97.018301

The time and venue remain the same as last week (see subject line).

With regards,

Ajay

Brownbag #78 (8/29, Fri, 12:30, YH2050)

Hello everyone,

This Friday at journal club we will discuss two papers related to the purification of ssRNA. The primary paper we will focus on is: "Rapid purification of RNAs using fast performance liquid chromatography (FPLC)" by I. Kim, S.A. McKenna, E.V. Puglisi and J.D. Puglisi, RNA 13 (2007) 289-294 (http://dx.doi.org/10.1261/rna.342607). The other paper is "Large-scale preparation and purification of polyacrylamide-free RNA oligonucleotides" by P.J. Lukavsky and J.D. Puglisi, RNA 10 (2004) 889-893 (http://dx.doi.org/10.1261/rna.5264804).

Brownbag #76 (5/23, Fri, 2:45pm, YH3047)

Hello everyone,

This Friday at journal club we will discuss the following paper (which
is the third paper in our series of three meetings on viral evolution):

* "The fittest versus the flattest: experimental confirmation of the
quasispecies effect with subviral pathogens" by F.M. Codoner, J.-A.
Daros, R.V. Sole and S.F. Elena, PLoS Pathogens 2, 1187-1193 (2006)
(http://dx.doi.org/10.1371/journal.ppat.0020136).

Some other interesting papers are:

Brownbag #75 (5/9, Fri, 2:45pm, YH3047)

Hello everyone,

Tomorrow at journal club we will discuss a combined experimental and
theoretical paper on DNA packaging in bacteriophage phi29:
"Three-dimensional architecture of the bacteriophage phi29 packaged
genome and elucidation of its packaging process" by L.R. Comolli et al,
Virology 371 (2008) 267-277 (http://dx.doi.org/10.1016/j.virol.2007.07.035).

See you tomorrow at 2:45 pm in Bill's office (YH3047).

Best,

Peter

Brownbag #74 (5/2, Fri, 2:45pm, YH3047)

Hello everyone,

This Friday we're meeting at 2:45 pm in Bill's office (YH3047) for journal club. We will discuss the following paper:

* "Complementation between Sindbis viral RNAs produces infectious
particles with a bipartite genome" by U. Geigenmuller-Gnirke, B.
Weiss, R. Wright and S. Schlesinger, PNAS 88, 3253-3257 (1991)
(http://www.pnas.org/cgi/reprint/88/8/3253).

Some other papers that might also be of interest for that meeting are:

Brownbag #73 (4/25, Fri, 1:30pm, YH3047)

Hello everyone,

During the last journal club meeting we decided on a couple of papers
for the next three meetings. At the next journal club meeting, on Friday
April 25th at 1:30 in Bill's office YH 3047 (note the new time and day),
we will discuss the following paper:

* "Western equine encephalitis virus is a recombinant virus" by C.S.
Hahn, S. Lustig, E.G. Strauss and J.H Strauss, PNAS 85, 5997-6001
(1988) (http://www.pnas.org/cgi/reprint/85/16/5997).

Brownbag #72 (3/27, Thur, 3:30pm, YH3047)

Hello everyone,

This week we will spend some more time looking at virus evolution and we
will focus specifically on RNA recombination. The paper we will discuss
is "Recombination in Alphaviruses" by James H. Strauss and Ellen G.
Strauss (Seminars in Virology 8 (1997) 85-94,
http://dx.doi.org/10.1006/smvy.1997.0115). Some other papers you might
want to look at (and that we might talk about as well) are: "RNA

Brownbag #71 (3/20, Thur, 3:30pm, YH3047)

Hello everyone,
This week we want to look at virus evolution and phylogeny. We will discuss the following paper at journal club: "Viruses' life history: towards a mechanistic basis of a trade-off between survival and reproduction among phages" by Marianne De Paepe and Francois Taddei (2006), PloS Biology 4 (7): e193.
The paper can be found here: http://dx.doi.org/10.1371/journal.pbio.0040193 .
Note that there is a mistake in the paper: in the abstract, the mortality rate is described as being negatively correlated with multiplication rate, whereas it is positively correlated. (see http://dx.doi.org/10.1371/journal.pbio.0040273). If you have any other interesting papers on virus evolution or phylogeny please bring them along.
See you this Thursday at 3:30 pm in Bill's office,
Peter

Brownbag #69 (2/20, Thur, 1:00pm, YH3047)

Hello everyone,

This Thursday at group meeting we will discuss a paper by Teryl Frey, David Gard and Jim Strauss about circle formation by RNA from Sindbis virus (J. Mol. Biol. 132 (1979) p 1 - 18). We will meet at 1 pm in Bill's office (YH3047).

Best,

Peter

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