Publications
2020
2020
- Beren, C., Cui, Y., Chakravarty, A., Yang, X., Knobler, C. M, Zhou, Z. H., Gelbart, W. M. (2020) Genome organization and interaction with capsid protein in a multipartite RNA virus. PNAS, 117 (20), 10673-80.
2019
2019
- Thurm, A. R., Beren, C., Duran-Meza, A. L., Knobler, C. M., Gelbart, W. M. (2019) RNA homopolymers form higher-curvature virus-like particles than do normal-composition RNAs. Biophysical Journal, 117 (7), 1331-41.
- Chung, S., Lerner, E., Jin, Y., Kim, S., Alhadid, Y., Grimaud, L. W., Zhang, I. X., Knobler, C. M., Gelbart, W. M., Weiss, S. (2019) The effect of macromolecular crowding on single-round transcription by Escherichia coli RNA polymerase. Nucleic Acids Research, 47 (3), 1440-50.
- Biddlecome, A., Habte, H. H., McGrath, K. M, Sambanthamoorthy, S., Wurm, M., Sykora, M. M., Knobler, C. M., Lorenz, I. C., Lasaro, M., Elbers, K., Gelbart, W. M. (2019) Delivery of self-amplifying RNA vaccines in in vitro reconstituted virus-like particles. PLoS ONE, 14 (6): e0215031.
2018
2018
- Garmann R. F., Knobler C. M., Gelbart W. M. (2018) Protocol for Efficient Cell-Free Synthesis of Cowpea Chlorotic Mottle Virus-Like Particles Containing Heterologous RNAs. In: Wege C., Lomonossoff G. (eds) Virus-Derived Nanoparticles for Advanced Technologies. Methods in Molecular Biology, vol 1776. Humana Press, New York, NY
- Chen, Y. J., Wu, D., Gelbart, W. M., Knobler, C. M., Phillips, R., Kegel, W. K. (2018) Two-Stage Dynamics of In Vivo Bacteriophage Genome Ejection. Phys. Rev. X, American Physical Society, 8, 021029.
2017
2017
- Beren, C., Dreesens, L. L., Liu, K. N., Knobler, C. M., & Gelbart, W. M. (2017). The effect of RNA secondary structure on the self-assembly of viral capsids. Biophysical journal, 113, 339-347.
- Chung, S., Lerner, E., Jin, Y., Kim, S., Alhadid, Y., Grimaud, L. W., . . . Weiss, S. (2017). The effect of macromolecular crowding on single-round transcription by E. coli RNA polymerase. bioRxiv, 218321.
2016
2016
- Borodavka, A., Singaram, S. W., Stockley, P. G., Gelbart, W. M., Ben-Shaul, A., & Tuma, R. (2016). Sizes of long RNA molecules are determined by the branching patterns of their secondary structures. Biophysical journal, 111, 2077-2085.
2015
2015
- Garmann, R. F., Gopal, A., Athavale, S. S., Knobler, C. M., Gelbart, W. M., & Harvey, S. C. (2015). Visualizing the global secondary structure of a viral RNA genome with cryo-electron microscopy. Rna, 21(5), 877-86.
- Ben-Shaul, A., & Gelbart, W. M. (2015). Viral ssRNAs are indeed compact. Biophysical journal, 108, 14-16.
- Garmann, R. F., Comas-Garcia, M., Knobler, C. M., & Gelbart, W. M. (2015). Physical principles in the self-assembly of a simple spherical virus. Accounts of chemical research, 49, 48-55.
- Jin, Y., Sdao, S. M., Dover, J. A., Porcek, N. B., Knobler, C. M., Gelbart, W. M., & Parent, K. N. (2015). Bacteriophage P22 ejects all of its internal proteins before its genome. Virology, 485, 128-134.
- Singaram, S. W., Garmann, R. F., Knobler, C. M., Gelbart, W. M., & Ben-Shaul, A. (2015). Role of RNA branchedness in the competition for viral capsid proteins. The Journal of Physical Chemistry B, 119, 13991-14002.
- Jin, Y., Knobler, C. M., & Gelbart, W. M. (2015). Controlling the extent of viral genome release by a combination of osmotic stress and polyvalent cations. Physical Review E, 92, 022708.
- Gelbart, W. M. (2015). DNA--peptide complexes: Regulation of interferon production. Nature materials, 14, 661.
- Garmann, R. F., Sportsman, R., Beren, C., Manoharan, V. N., Knobler, C. M., & Gelbart, W. M. (2015). A simple RNA-DNA scaffold templates the assembly of monofunctional virus-like particles. Journal of the American Chemical Society, 137, 7584-7587.
2014
2014
- Gopal, A., Egecioglu, D. E., Yoffe, A. M., Ben-Shaul, A., Rao, A. L., Knobler, C. M., & Gelbart, W. M. (2014). Viral RNAs are unusually compact. PLoS One, 9, e105875.
- Comas-Garcia, M., Garmann, R. F., Singaram, S. W., Ben-Shaul, A., Knobler, C. M., & Gelbart, W. M. (2014). Characterization of viral capsid protein self-assembly around short single-stranded RNA. The Journal of Physical Chemistry B, 118, 7510-7519.
- Garmann, R. F., Comas-Garcia, M., Koay, M. S., Cornelissen, J. J., Knobler, C. M., & Gelbart, W. M. (2014). The role of electrostatics in the assembly pathway of a single-stranded RNA virus. Journal of virology, JVI--01044.
- Garmann, R. F., Comas-Garcia, M., Gopal, A., Knobler, C. M., & Gelbart, W. M. (2014). The assembly pathway of an icosahedral single-stranded RNA virus depends on the strength of inter-subunit attractions. Journal of molecular biology, 426, 1050-1060.
- Vega-Acosta, J. R., Cadena-Nava, R. D., Gelbart, W. M., Knobler, C. M., & Ruiz-Garcı́a, J. (2014). Electrophoretic mobilities of a viral capsid, its capsid protein, and their relation to viral assembly. The Journal of Physical Chemistry B, 118, 1984-1989.
2013
2013
- Azizgolshani, O., Garmann, R. F., Cadena-Nava, R., Knobler, C. M., & Gelbart, W. M. (2013). Reconstituted plant viral capsids can release genes to mammalian cells. Virology, 441, 12-17.
2012
2012
- Cadena-Nava, R. D., Comas-Garcia, M., Garmann, R. F., Rao, A. L., Knobler, C. M., & Gelbart, W. M. (2012). Self-assembly of viral capsid protein and RNA molecules of different sizes: requirement for a specific high protein/RNA mass ratio. Journal of virology, 86, 3318-3326.
- Gopal, A., Zhou, Z. H., Knobler, C. M., & Gelbart, W. M. (2012). Visualizing large RNA molecules in solution. Rna, 18, 284-299.
- Gelbart, W. M., Ben-Shaul, A., & Roux, D. (2012). Micelles, membranes, microemulsions, and monolayers. Springer Science & Business Media.
- Comas-Garcia, M., Cadena-Nava, R. D., Rao, A. L., Knobler, C. M., & Gelbart, W. M. (2012). In vitro quantification of the relative packaging efficiencies of single-stranded RNA molecules by viral capsid protein. Journal of virology, JVI--01695.
2011
2011
- Fang, L. T., Gelbart, W. M., & Ben-Shaul, A. (2011). The size of RNA as an ideal branched polymer. The Journal of chemical physics, 135, 10B616.
- Snyder, J. E., Azizgolshani, O., Wu, B., He, Y., Lee, A. C., Jose, J., Suter, D. M., Knobler, C. M., Gelbart, W. M., Kuhn, R. J. (2011). Rescue of Infectious Particles from Pre-assembled Alphavirus Nucleocapsid Cores. Journal of virology.
- Fang, L. T., Yoffe, A. M., Gelbart, W. M., & Ben-Shaul, A. (2011). A sequential folding model predicts length-independent secondary structure properties of long ssRNA. The Journal of Physical Chemistry B, 115, 3193-3199.
- Cadena-Nava, R. D., Hu, Y., Garmann, R. F., Ng, B., Zelikin, A. N., Knobler, C. M., & Gelbart, W. M. (2011). Exploiting fluorescent polymers to probe the self-assembly of virus-like particles. The Journal of Physical Chemistry B, 115, 2386-2391.
- Qiu, X., Rau, D. C., Parsegian, V. A., Fang, L. T., Knobler, C. M., & Gelbart, W. M. (2011). Salt-dependent DNA-DNA spacings in intact bacteriophage λ reflect relative importance of DNA self-repulsion and bending energies. Physical review letters, 106, 028102.
2010
2010
- Yoffe, A. M., Prinsen, P., Gelbart, W. M., & Ben-Shaul, A. (2010). The ends of a large RNA molecule are necessarily close. Nucleic acids research, 39, 292-299.
- Prinsen, P., Schoot, P., Gelbart, W. M., & Knobler, C. M. (2010). Multishell structures of virus coat proteins. The Journal of Physical Chemistry B, 114, 5522-5533.
- Knobler, C. M., & Gelbart, W. M. (2010). What Determines the Size of an RNA Virus? In Emerging Topics in Physical Virology (pp. 185-215). World Scientific.
2009
2009
- Knobler, C. M., & Gelbart, W. M. (2009). Physical chemistry of DNA viruses. Annual review of physical chemistry, 60, 367-383.
- Gelbart, W. M., & Knobler, C. M. (2009). Pressurized viruses. Science, 323, 1682-1683.
- Prinsen, P., Fang, L. T., Yoffe, A. M., Knobler, C. M., & Gelbart, W. M. (2009). The force acting on a polymer partially confined in a tube. The Journal of Physical Chemistry B, 113, 3873-3879.
- Lavelle, L., Gingery, M., Phillips, M., Gelbart, W. M., Knobler, C. M., Cadena-Nava, R. D., Vega-Acosta, J. R., Pinedo-Torres, L. A., Ruiz-Garcia, J. (2009). Phase diagram of self-assembled viral capsid protein polymorphs. The Journal of Physical Chemistry B, 113, 3813-3819.
2008
2008
- Yoffe, A. M., Prinsen, P., Gopal, A., Knobler, C. M., Gelbart, W. M., & Ben-Shaul, A. (2008). Predicting the sizes of large RNA molecules. Proceedings of the National Academy of Sciences.
- Hu, Y., Zandi, R., Anavitarte, A., Knobler, C. M., & Gelbart, W. M. (2008). Packaging of a polymer by a viral capsid: the interplay between polymer length and capsid size. Biophysical journal, 94, 1428-1436.
- Chang, C. B., Knobler, C. M., Gelbart, W. M., & Mason, T. G. (2008). Curvature dependence of viral protein structures on encapsidated nanoemulsion droplets. Acs Nano, 2, 281-286.
- Gelbart, W. M., & Knobler, C. M. (2008). The physics of phages. Physics today, 61, 42.
2006
2006
- Nguyen, T. T., Bruinsma, R. F., & Gelbart, W. M. (2006). Continuum theory of retroviral capsids. Physical review letters, 96, 078102.
- Inamdar, M. M., Gelbart, W. M., & Phillips, R. (2006). Dynamics of DNA ejection from bacteriophage. Biophysical journal, 91, 411-420.
- Grayson, P., Evilevitch, A., Inamdar, M. M., Purohit, P. K., Gelbart, W. M., Knobler, C. M., & Phillips, R. (2006). The effect of genome length on ejection forces in bacteriophage lambda. Virology, 348, 430-436.
2005
2005
- Nguyen, T. T., Bruinsma, R. F., & Gelbart, W. M. (2005). Elasticity theory and shape transitions of viral shells. Physical Review E, 72, 051923.
- Bagatella-Flores, N., Schiessel, H., & Gelbart, W. M. (2005). Statics and dynamics of polymer-wrapped colloids. The Journal of Physical Chemistry B, 109, 21305-21312.
- Borukhov, I., Bruinsma, R. F., Gelbart, W. M., & Liu, A. J. (2005). Structural polymorphism of the cytoskeleton: a model of linker-assisted filament aggregation. Proceedings of the National Academy of Sciences, 102, 3673-3678.
- Evilevitch, A., Gober, J. W., Phillips, M., Knobler, C. M., & Gelbart, W. M. (2005). Measurements of DNA lengths remaining in a viral capsid after osmotically suppressed partial ejection. Biophysical journal, 88, 751-756.
2004
2004
- Castelnovo, M., & Gelbart, W. M. (2004). Semiflexible chain condensation by neutral depleting agents: role of correlations between depletants. Macromolecules, 37, 3510-3517.
- Tzlil, S., Deserno, M., Gelbart, W. M., & Ben-Shaul, A. (2004). A statistical-thermodynamic model of viral budding. Biophysical journal, 86, 2037-2048.
- Zandi, R., Reguera, D., Bruinsma, R. F., Gelbart, W. M., & Rudnick, J. (2004). Origin of icosahedral symmetry in viruses. Proceedings of the National Academy of Sciences, 101, 15556-15560.
- Lee, K.-C., Borukhov, I., Gelbart, W. M., Liu, A. J., & Stevens, M. J. (2004). Effect of mono-and multivalent salts on angle-dependent attractions between charged rods. Physical review letters, 93, 128101.
- Evilevitch, A., Castelnovo, M., Knobler, C. M., & Gelbart, W. M. (2004). Measuring the force ejecting DNA from phage. The Journal of Physical Chemistry B, 108, 6838-6843.
2003
2003
- Evilevitch, A., Lavelle, L., Knobler, C. M., Raspaud, E., & Gelbart, W. M. (2003). Osmotic pressure inhibition of DNA ejection from phage. Proceedings of the National Academy of Sciences, 100, 9292-9295.
- Zandi, R., Reguera, D., Rudnick, J., & Gelbart, W. M. (2003). What drives the translocation of stiff chains? Proceedings of the National Academy of Sciences, 100, 8649-8653.
- Cordova, A., Deserno, M., Gelbart, W. M., & Ben-Shaul, A. (2003). Osmotic shock and the strength of viral capsids. Biophysical journal, 85, 70-74.
- Bruinsma, R. F., Gelbart, W. M., Reguera, D., Rudnick, J., & Zandi, R. (2003). Viral self-assembly as a thermodynamic process. Physical review letters, 90, 248101.
- Tzlil, S., Kindt, J. T., Gelbart, W. M., & Ben-Shaul, A. (2003). Forces and pressures in DNA packaging and release from viral capsids. Biophysical journal, 84, 1616-1627.
- Castelnovo, M., Bowles, R. K., Reiss, H., & Gelbart, W. M. (2003). Osmotic force resisting chain insertion in a colloidal suspension. The European Physical Journal E, 10, 191-197.
2002
2002
- Borukhov, I., Lee, K.-C., Bruinsma, R. F., Gelbart, W. M., Liu, A. J., & Stevens, M. J. (2002). Association of two semiflexible polyelectrolytes by interchain linkers: theory and simulations. The Journal of chemical physics, 117, 462-480.
- Deserno, M., & Gelbart, W. M. (2002). Adhesion and wrapping in colloid- vesicle complexes. The Journal of Physical Chemistry B, 106, 5543-5552.
2001
2001
- Kindt, J., Tzlil, S., Ben-Shaul, A., & Gelbart, W. M. (2001). DNA packaging and ejection forces in bacteriophage. Proceedings of the National Academy of Sciences, 98, 13671-13674.
- Schiessel, H., Bruinsma, R. F., & Gelbart, W. M. (2001). Electrostatic complexation of spheres and chains under elastic stress. The Journal of Chemical Physics, 115, 7245-7252.
- Schiessel, H., Widom, J., Bruinsma, R. F., & Gelbart, W. M. (2001). Polymer reptation and nucleosome repositioning. Physical review letters, 86, 4414.
- Schiessel, H., Gelbart, W. M., & Bruinsma, R. (2001). DNA folding: structural and mechanical properties of the two-angle model for chromatin. Biophysical Journal, 80, 1940-1956.
- Borukhov, I., Bruinsma, R. F., Gelbart, W. M., & Liu, A. J. (2001). Elastically driven linker aggregation between two semiflexible polyelectrolytes. Physical review letters, 86, 2182.
- Kindt, J. T., & Gelbart, W. M. (2001). Chain self-assembly and phase transitions in semiflexible polymer systems. The Journal of Chemical Physics, 114, 1432-1439.
- Gelbart, W. M. (2001). DNA Condensation and Complexation. In Electrostatic effects in soft matter and biophysics (pp. 53-86). Springer.
2000
2000
- Gelbart, W. M., Bruinsma, R. F., Pincus, P. A., & Parsegian, V. A. (2000). DNA-inspired electrostatics. Physics today, 53, 38-45.
- Schiessel, H., Rudnick, J., Bruinsma, R., & Gelbart, W. M. (2000). Organized condensation of worm-like chains. EPL (Europhysics Letters), 51, 237.
- Lambert, O., Letellier, L., Gelbart, W. M., & Rigaud, J.-L. (2000). DNA delivery by phage as a strategy for encapsulating toroidal condensates of arbitrary size into liposomes. Proceedings of the National Academy of Sciences, 97, 7248-7253.